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Understanding Peritoneal Mesothelioma

Peritoneal mesothelioma is a rare and often misunderstood cancer that forms in the lining of the abdomen (the peritoneum).

While hearing a peritoneal mesothelioma diagnosis can feel overwhelming for patients and loved ones, it is the type of mesothelioma with the most promising outcomes.

Advancements in treatments including surgery combined with heated chemotherapy (HIPEC), have significantly improved survival rates, offering real hope to patients and their families.

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“If you're diagnosed with mesothelioma, move on it, and do it immediately, because it's important. We don't know how much time we have.”

Steve, Mesothelioma Patient & Resource Recipient

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The 4 Stages of Peritoneal Mesothelioma

Unlike pleural mesothelioma, peritoneal mesothelioma does not have a formal four-stage system.

Instead, many specialists use the Peritoneal Cancer Index (PCI) to evaluate the extent of cancer spread within the abdomen, which helps guide treatment options.

Peritoneal mesothelioma has more available treatments and overall better outcomes when detected early, while the cancer remains small and localized.

Acting quickly after a diagnosis is necessary to maximize treatment options.

"My husband Marty had mesothelioma long before he was diagnosed and he was stage 4."

Marge, Wife of Mesothelioma Patient Marty

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How Peritoneal Mesothelioma Is Treated

Mesothelioma treatment options are tailored to each patient’s unique diagnosis, focusing on improving outcomes, managing symptoms, and enhancing quality of life. Mesothelioma treatment can include:

Surgery

Palliative Procedures

Radiation Therapy

Chemotherapy

Immunotherapy

Targeted Therapy

Multimodal Therapy

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Reminder: About 30% of All Mesothelioma Patients Are Veterans

Access resources and support set aside exclusively for mesothelioma patients who served our country:

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"60 years ago I was exposed to asbestos in the Navy."

John,  Mesothelioma Patient in Florida, Navy Veteran

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Peritoneal Mesothelioma Survival Rates

Survival rates for peritoneal mesothelioma vary widely based on many key factors, including the cancer spread at diagnosis, cell type, and the patient’s overall health.


While a peritoneal mesothelioma prognosis can feel challenging, early detection and advancements in treatment options have led to improved outcomes for many patients. Innovative therapies and personalized treatment plans offer hope.


The average survival rates for peritoneal mesothelioma across the U.S. are:  

One-year survival rate: 92% 
Three-year survival rate: 74% 
Five-year survival rate: 65% 
Ten-year survival rate: 39% 
 
But please note: survival rates are just an average and do not take into account personalized treatments. 

One inspiring example is the longest-known peritoneal mesothelioma survivor, who lived over 25 years after being given only a few weeks to live.

“When they tell you: you have cancer, everything changes. They gave me hope.”

Robert, Mesothelioma Patient & Resource Recipient in Florida

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How Peritoneal Mesothelioma Is Treated

Mesothelioma treatment options are tailored to each patient’s unique diagnosis, focusing on improving outcomes, managing symptoms, and enhancing quality of life. Mesothelioma treatment can include:

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MESOTHELIOMALUNG CANCERASBESTOSISSTILL TESTING
Peritoneal mesothelioma is a rare and aggressive cancer that forms in the lining of the abdomen, called the peritoneum.

It is caused by exposure to asbestos, a harmful mineral once widely used in construction and manufacturing..

Peritoneal mesothelioma often develops decades after asbestos exposure, and while it can feel overwhelming, advancements in treatment offer hope for many patients and their families.
Mesothelioma is categorized as different types based on where it develops in the body.

The other types of mesothelioma are:

• Pleural mesothelioma (lungs): The most common type of mesothelioma affecting the chest and lungs

• Pericardial mesothelioma (heart): A very rare type which develops around the heart

• Testicular mesothelioma (testes): The rarest type, affecting the lining of the testes.

Knowing the type of mesothelioma is important as it can help you determine the best treatment options available and which specialists to see.
To confirm peritoneal mesothelioma, a biopsy is most often performed, where a tissue sample from the affected area is examined under a microscope for cancer cells.

Before a biopsy, doctors often use imaging tests like X-rays, CT scans, or MRIs to detect abnormalities and determine the best area for tissue sampling.

The most common biopsy method for peritoneal mesothelioma is a laparoscopy, where a thin flexible instrument with a light and camera (a laparoscope) is inserted into the abdomen to collect tissue samples for an accurate diagnosis.

If you or a loved one has been diagnosed with mesothelioma, it’s important to seek expert guidance as soon as possible. Early diagnosis offers a wider range of treatment options and can improve outcomes.
Yes, it’s always a good idea to get a second opinion.

Peritoneal mesothelioma is a rare and complex disease and consulting a specialist can provide clarity, reassurance, and confidence in your next steps.

A second opinion may also introduce new treatment options or approaches that better fit you and your family’s needs.
Out-of-pocket costs for peritoneal mesothelioma treatment can be incredibly high for surgery, chemotherapy, and other care.

But you’re not alone—financial assistance is available. Common options include legal claims for asbestos exposure, veterans’ benefits, and support from insurance or financial aid programs.

You can call our number and one of our patient advocates will help you discover what’s available for you and we’ll do our best to support you in reducing your financial stress and burden.
Finding a peritoneal mesothelioma specialist is critical for receiving the best care. These experts are often found at leading cancer centers around the U.S. and have experience treating this rare disease.

Your doctor can likely help provide a referral or call us and our patient advocates can help connect you to the peritoneal mesothelioma specialists best suited for you or your loved one’s specific needs.
Many veterans were exposed to asbestos during their military service, particularly between the 1930s and 1970s, when asbestos was heavily used in Navy ships, military buildings, aircrafts, and vehicles.

This exposure puts veterans at a higher risk of developing mesothelioma, a disease that can take decades to appear after initial exposure.

Veterans account for about 30% of all mesothelioma patients. Fortunately, there are additional veterans benefits and specialized care programs designed to support veterans and their families through this difficult journey.

Please call us if you need answers to mesothelioma veteran related questions.
The cancer is in its original location (such as the lining of a lung) and has not spread to lymph nodes or other tissues. Stage one offers the most treatment options and the best prognosis.
The cancer has started to spread to nearby lymph nodes or deeper into the lung but remains close to the original location. Treatment may still aim to manage or potentially remove much of the cancer.
The cancer has spread more extensively to nearby tissues, organs, or lymph nodes. For pleural mesothelioma, this may include areas like the chest wall, making treatment more complex but still focused on extending survival and improving quality of life.
At this stage, the cancer has spread (metastasized) to distant parts of the body, such as other organs. Treatment focuses on managing symptoms, providing comfort, and improving quality of life, rather than than attempting to control or significantly reduce the cancer.

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